Is This Unspoken of Hormone Blocking You From Losing Those Last 5 Kilos? August 2, 2016 Video Is This Unspoken of Hormone Blocking You From Losing Those Last 5 Kilos? Struggling to lose those last 5 kilos? Leptin resistance may be the culprit. Leptin is an unspoken of hormone responsible for regulating appetite. In this video, Travelling Dietitian, Kara Landau, shares five things you can do to help prevent leptin resistance and lose those last few stubborn kilos.